Homosexuality, sex work and abortion are all illegal in Uganda, making it difficult for young people affected by HIV.
The Alliance is rebuilding lives with methadone programmes and reducing the spread of HIV through needle exchange.
Young people are finding ways to talk about sex, HIV and violence against girls in a society that often silences these topics.
For HIV positive women, giving birth is dangerous. A community mapping project identified women at risk and provided support.
Community volunteers are changing things for local people affected by HIV and more people are going for counseling and family planning.
Many fishermen cope with the harsh reality of life at sea by injecting heroin. A needle exchange service is transforming a community.
VIDEO: Frank Mugisha, Executive Director of Sexual Minorities Uganda, talking about the challenges in fighting for LGBT rights in Uganda.
Men who have sex with men and sex workers are highly stigmatized, but working through community animators helps to meet their needs.
Sex workers are reaching out to each other, offering support, condoms and referrals to health clinics for HIV counselling and testing.
Working with transgender women and sex workers means they get more involved with policies and have better access to programmes and services.
Violence, murder and human rights abuses are taking place against transgender women in Latin America. Activists are speaking out.
Men who have sex with men are criminalized in Morocco and it takes a lot for them to trust anyone. One organisation is reaching out to them.